I'm not quite sure what to say about your post.
It really does depend on the design technique used in the crease pattern and your folding style.
If you want to learn about box pleating, hex pleating, and circle river packing, ODS is the book for you. However, it has nothing on 22.5 degree designing, and relatively little on designing with traditional bases.
I have yet to find a good source of information on designing using 22.5 degrees.
For crease patterns, having designed some yourself does help because it makes it easier to recognize common molecules and techniques, which can help in the folding. If you want to practice box pleating crease patterns, there are a lot of places available. For 22.5 degree, check out Gen Hagiwara's flickr page.
I have not yet purchased Creating Origami so I can't say anything about that.
I hoped this helped
